Lysis Solution (HP2) is supplied by HiMedia. It contains SDS.

• Molecular Formula: C₁₂H₂₅NaO₄S

• Molecular Weight: 288.38

Cell lysis solutions are detergent-based, buffers and reagent solutions that have been optimized for particular cell lysis applications. Effective cell lysis and protein extraction for different species of organisms and different cell and tissue types require different buffer formulations. Detergent cell lysis is a milder and easier alternative to physical disruption of cell membranes, although it is often used in conjunction with homogenization and mechanical grinding. Detergents break the lipid barrier surrounding cells by solubilizing proteins and disrupting lipid–lipid, protein–protein and protein–lipid interactions. Detergents, like lipids, self-associate and bind to hydrophobic surfaces. They are comprised of a polar hydrophilic head group and a nonpolar hydrophobic tail, and are categorized by the nature of the head group as either ionic (cationic or anionic), nonionic, or zwitterionic. Their behavior depends on the properties of the head group and tail.