Antibiotic Susceptibility Tests are conducted in microbiological laboratories to study the effect of an antibiotic on the growth of a microbe. The most common method to study antibiotic susceptibility includes the Kirby-Bauer Method. In this method, small discs saturated with antibiotic is placed on the plate containing the bacteria. A zone of inhibition of growth around the disc is observed to study the susceptibility of the microbe to the antibiotic. Aztreonam- AT-30mcg is a product by Micromaster. It is an antibacterial antibiotic. Aztreonam shows activity against gram-negative bacterial species. It is administered for the treatment of diseases such as, urinary tract infections, endometritis, bone infections, etc. It is found to be active against, Staphylococcus aureus, Staphylococcus pyogenes, Staphylococcus epidermis, Citrobacter, Proteus, Klebsiella, etc. The drug inhibits bacterial cell wall synthesis. It blocks the synthesis of a molecule called muropeptide, which is essential to peptidoglycan cross-linking in the bacterial cell wall. The drug has some level of bactericidal activity also.
Specifications:
Product name: Aztreonam- AT-30mcg
Brand: Micromaster
Molecular formula: C13H17N5O8S2
Molecular mass: 435.433 g/mol
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